What is a granular growth or tumor?

Granular cell tumors (GCTs) are soft tissue tumors that can occur anywhere in the body. They are thought to arise from the cells that surround and insulate the nerve cells in our body (Schwann cells). Most granular cell tumors are benign (non-cancerous), although some may be locally aggressive.

What is the origin of granular cell tumor?

A granular cell tumour is an uncommon, generally benign tumour previously known as granular cell myoblastoma. Their origin has been debated since their first description, but it is now generally believed they originate from Schwann cells (cells that provide myelin insulation to nerves).

What is a granular in the mouth?

The granular cell tumor (GCT) is a rare, benign tumor that most commonly occurs in the oral cavity, particularly in the anterior part of the tongue.

What kind of cancer is a granular cell tumor?

Most granular cell tumors are benign (non-cancerous), although some may be locally aggressive. Less than 2% are malignant (cancerous), but these are aggressive and often are associated with a poor prognosis. GCTs a ffect females more often than males and usually present as a solitary painless mass. A few individuals have multiple GCTs.

Can a granular cell tumor of the colon be harmful?

Granular Cell Tumors of Colon is normally not harmful, due to their benign nature. Therefore, any complications arising from such polyps are typically minimal Nevertheless, in rare cases, GCT of Colon may be malignant. In such cases, the tumor may spread to others part of the body

Is the removal of a granular cell tumor curative?

Complete surgical removal of the tumor is usually curative, but in some cases the tumors may recur. [4] Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services.

What are the adverse prognostic factors for granular cell cancer?

Adverse prognostic factors include local recurrence, metastasis, larger tumor size, older patient age, histologic classification as malignant, presence of necrosis, increased mitotic activity, spindling of tumor cells, vesicular nuclei with large nucleoli and Ki67 ≥ 10% ( Am J Surg Pathol 1998;22:779 )