What antibiotics treat Mycobacterium Marinum?

marinum is oral antibiotics. Clarithromycin with ethambutol is currently the preferred antibiotic selection. Rifampin is typically added to the antibiotics regimen if deeper organ infection is present, such as bone infection (osteomyelitis).

How do you test for Mycobacterium Marinum?

Polymerase chain reaction (PCR) amplification techniques using Mycobacterium genus-specific primers can be used to diagnose M marinum infection directly in the biopsy sample. Tuberculin skin test using purified protein derivative is positive in 67%-100% of cases.

What antibiotics cover Mycobacterium?

Doctors typically recommend a combination of three to four antibiotics, such as clarithromycin, azithromycin, rifampin, rifabutin, ethambutol, streptomycin, and amikacin.

How is Mycobacterium spread?

M. tuberculosis is carried in airborne particles, called droplet nuclei, of 1– 5 microns in diameter. Infectious droplet nuclei are generated when persons who have pulmonary or laryngeal TB disease cough, sneeze, shout, or sing. TB is spread from person to person through the air.

What disease causes Mycobacterium Marinum?

Mycobacterium marinum is a non-tuberculous mycobacterium that causes a tuberculosis-like illness in fish and can infect humans when injured skin is exposed to a contaminated aqueous environment.

What is the drug of choice for treating mycobacterial infections?

Doctors typically recommend a combination of three to four antibiotics, such as clarithromycin, azithromycin, rifampin, rifabutin, ethambutol, streptomycin, and amikacin. They use several antibiotics to prevent the mycobacteria from becoming resistant to any one medication.

How long does it take to treat M marinum infection?

The mainstay of treatment in M marinum infection is antimicrobial therapy. The duration of therapy is not well defined, but treatment of skin and soft-tissue infections should be continued for 1-2 months after resolution of symptoms and lesions. Therefore, the treatment duration is typically 3-4 months, longer if deeper structures are involved.

Is there any cure for Mycobacterium marinum?

Treatment of M. marinum has not been systematically studied. Some cases demonstrate spontaneous healing. In others, healing may occur with the administration of antimicrobial agents including minocycline, clarithromycin, rifampin or ethambutol.

When to use surgical debridement for marinum infection?

Most cases of invasive M. marinum infection require surgical debridement, 69% in this series. This approach seems particularly appropriate in immunocompromised patients, those with tenosynovitis, or those for whom medical therapy fails.

What kind of infections can m.marinum cause?

M. marinum can also cause infections in fish. Human infections are seen in low, but consistent numbers. The risk of infection increases for people who have a scrape, cut or other skin abrasion that can serve as an entry site for the bacteria and come into direct contact with a contaminated water source.