Do antidepressants contribute to bone loss?
Do antidepressants contribute to bone loss?
One of the side effects of using antidepressant medications of the SSRI class (selective serotonin reuptake inhibitors) may be an increased risk of bone loss and fractures.
How do SSRIs affect bone density?
SSRI use is associated with decreased femoral and lumbar BMD. Use of SSRIs and TCAs was not associated with an increased rate of bone loss at the spine, total hip or femoral neck. 3.2% lower BMD in SSRI users as compared to nonusers.
Which medications affect bone density?
Other medicines that may cause bone loss
| Medicine | Used For |
|---|---|
| Loop diuretics such as furosemide and torsemide | Heart failure, edema (tissue swelling), some kidney problems |
| Medroxyprogesterone acetate | Contraception |
| Methotrexate | Cancer and rheumatoid arthritis |
| Thiazolidinediones such as pioglitazone and rosiglitazone | Diabetes |
Is sertraline bad for your bones?
Antidepressant medications that are Selective Serotonin Reuptake Inhibitors (SSRIs), such as Paxil (Paroxetine), Celexa (Citalopram), Prozac (Fluoxetine), Luvox (Fluvoxamine), and Zoloft (Sertraline), have been reported to increase the risk of bone fractures in men and women by 50-70%.
What medications interfere with calcium absorption?
Iron Supplements (calcium should not be taken at the same time as iron)
Which antidepressants increase the risk of osteoporosis?
Some of these have been linked to decreased BMD (SSRIs) and increased fracture risk (SSRIs and tricyclic agents). Current use of SSRIs and tricyclics increases fracture risk by as much as twofold versus nonusers, even after adjustment for potential confounders.
Can you reverse osteoporosis without drugs?
Can osteoporosis be reversed without medications? Your doctor diagnoses osteoporosis based on bone density loss. You can have different degrees of the condition, and catching it early can help you prevent the condition from worsening. You cannot reverse bone loss on your own.
How can I rebuild my bones?
5 Ways to Strengthen Older Bones
- Exercise. Just 30 minutes of exercise each day can help strengthen bones and prevent osteoporosis.
- Eat a balanced diet.
- Take supplements.
- Make sure your body absorbs the calcium and vitamin D it needs.
- Avoid salty foods and caffeinated beverages.
- Get a bone density scan.
What shouldn’t you take with calcium?
Take your calcium supplements with meals, rather than alone. The calcium needs the acid from stomach juices to break it down. Avoid taking calcium supplements with very high fiber meals. Fiber can bind with calcium, reducing the amount available to your body.
How are antidepressants linked to bone mineral density?
About 3% of the men were taking SSRIs, and about 3% were taking other antidepressants. Bone mineral density among SSRI users was 3.9% lower at the hip and 5.6% lower in the spine than in the other participants.
Are there any links between osteoporosis and antidepressants?
A substantial proportion of depressed patients receive antidepressants, mostly selective serotonin reuptake inhibitors (SSRIs). Some of these have been linked to decreased BMD (SSRIs) and increased fracture risk (SSRIs and tricyclic agents).
Are there any medications that are bad for your bones?
This particular antidepressant medication increases fracture risk and bone loss in older women and is associated with lower bone density in children and men. Additional steps your health care provider may take when you start an antidepressant.
Why do so many people take antidepressants?
A range of aspects of depression may operate, including behavioral factors (e.g., smoking and nutrition), biological changes, and confounders (e.g., comorbidities and concomitant medications). A substantial proportion of depressed patients receive antidepressants, mostly selective serotonin reuptake inhibitors (SSRIs).